Background: Beta thalassemia is the most common genetic disorder in Pakistan.Thalassemia is a preventive disease a fact well demonstrated by Softshell Bodywarmers countries such as Italy, Greece and Cyprus.Thalassemia prevention program especially prenatal diagnosis has been successfully introduced in Pakistan since 1994.Aims and Objectives: After
Podocytes are terminally differentiated glomerular epithelial cells.Podocyte loss has been found in many renal diseases.Cdk5 is a cyclin-dependent protein kinase which is predominantly regulated by p35.To study the role of Cdk5/p35 in podocyte survival, we first applied western blotting (WB) analysis to confirm the time-course expression of Cdk5 an
We report a 41 year old male with sickle cell disease who developed a myelodysplastic syndrome and acute myeloid leukemia Trim Ring Kit with complex karyotype involving chromosomes 5, 7 and 17 after 15 years of hydroxyurea treatment.He responded poorly to induction chemotherapy with cytarabine/idarubicin followed by high dose cytarabine and succumb
Abstract Ecological thresholds, which represent points of rapid change Mountaineering - Homme - Chaussures in ecological properties, are of major scientific and societal concern.However, very little research has focused on empirically testing the occurrence of thresholds in temperate terrestrial ecosystems.To address this knowledge gap, we tested w
Ongoing anthropogenic eutrophication and warming temperatures are expected to increase the extent and severity of hypoxia globally.Monitoring hypoxia has traditionally relied on costly surveys or sensor networks.While benthic macroinvertebrates are valuable indicators of hypoxia, community analysis is limited by small spatial scales of traditional